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What is Zestril used for?

Zestril (lisinopril) is an ACE (angiotensin converting enzyme) inhibitor used for the treatment of congestive heart failure and high blood pressure, as well as to improve the chances of survival after the patient experienced a heart attack.

Before you start taking this drug

Always talk to your doctor before you start using Zestril and report any medical conditions you think may be important. Some medical conditions may require a dose adjustment or additional monitoring, as otherwise there is a risk they can reduce the efficiency of Zestril treatment. The following health issues will need to be discussed with your doctor: diabetes, congestive heart failure, connective tissue disorder, liver disease, kidney disease, or heart disease. Make sure you tell your doctor if you are pregnant before starting the treatment, as Zestril can affect your baby very seriously. If you have ever been allergic to ACE inhibitors, such as fosinopril, moexipril, captopril, trandolapril, quinapril, benazepril, enalapril, ramipril or perindopril, do not take Zestril, as the same reaction will be experienced again.

How to start the treatment

Make sure you follow all the directions of your doctor or those on the label when using Zestril for your health problem. Your dose may need to be changed occasionally for you to get all the benefits of the treatment. Make sure you take each dose of Zestril with a glass of water, with some food or without. You will need to avoid drinking any amounts of alcohol, as it can lower your blood pressure and intensify some of the side effects Zestril causes. Potassium supplements or salt substitutes can be used in the course of the treatment, but only if you have been recommended to do so by your health care provider. Some of the effects Zestril causes, such as diarrhea, vomiting and excessive sweating can lead to easy dehydration. Dehydration may be dangerous as it can cause electrolyte disorders, kidney failure or low blood pressure. You will need to get plenty of fluids during the day to make sure your Zestril treatment is safe and efficient. Your doctor will need to measure your blood pressure, as well as kidney or liver function, to make sure you are benefitting from taking Zestril and can carry on with the treatment. Make sure you carry on with the treatment even if you feel better, especially if you are using Zestril for high blood pressure. High blood pressure often has no symptoms, but is nevertheless very dangerous.

Is Zestril overdose dangerous?

If you accidentally or intentionally used too much of Zestril, seek emergency medical help and report any symptoms that appear after the overdose. The following are possible symptoms in case of an overdose: light-headedness, extreme dizziness, or fainting.

Side effects of Zestril treatment

You will need to be aware of some mild and more serious side effects of Zestril that will need to be either reported to your doctor or watched closely to make sure they disappear on their own. Such mild side effects of Zestril as vomiting, dizziness, drowsiness, diarrhea, mild rash, headache, mild skin itching, nausea, cough, upset stomach, or depressed mood can be safely ignored as long as they go away on their own and do not cause any additional problems. On the other hand, such serious side effects of Zestril as pounding or uneven heartbeats, swelling, tired feeling, fainting, chills, fever, feeling light-headed, urinating more or less than usual, rapid weight gain, body aches, flu symptoms, muscle weakness or chest pain are to be reported as soon as you get them.

How serious are Zestril drug interactions?

Any drugs you are using will be important to report, as that way you may be able to avoid interactions. Please make sure you tell your doctor if at the moment of starting Zestril treatment you are also using salt substitutes, diuretics, lithium, non-steroidal anti-inflammatory drugs such as aspirin, potassium supplements, insulin or diabetes medications, gold injections to treat arthritis.

Zestril FDA category

Zestril is FDA pregnancy category D: it can cause birth defects in the unborn baby. You will need to tell your doctor if you are pregnant at the moment of starting the treatment and talk to your doctor as soon as possible if you think you may have become pregnant in the course of the treatment. It will be important for you to use an effective form of birth control to avoid a pregnancy and make sure there is no harm for your baby. The effects of Zestril in nursing infants are not known, as it was not established if it passes into breast milk or not.

Can Zestril be shared with other patients?

Make sure you never share your dose of Zestril with other people, as they may not benefit from the treatment as much as you expect. Store Zestril in some place where it will not be accessed by other people, especially small children.