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Xenical
Xenical is a medication prescribed to those who aim at losing weight and want to keep it from returning to its past state. Working by slowing down the enzymes that break down fat, which results in lower absorption of fat by the body, Xenical capsules are taken with each meal that has fatty food in its content. The drug also has some potential to produce side effects such as gas, stomach pain and urgent need to have a bowel movement.
What Is Xenical And What Is It Used for?
Xenical® (orlistat) is a drug available on prescription, used in the weight-loss therapy. It stimulates the process of losing weight, and is also effective at preventing people from gaining it back.
Who Manufactures Xenical?
Xenical is currently produced by Roche Pharmaceuticals.
In What Way Does Xenical Work?
The main effect Xenical has is decreasing the amount of fat absorbed by the body from the diet. It binds lipases, the enzymes of the stomach and intestine, which are responsible for breaking fat into smaller molecules which are later absorbed. While the activity of lipases is inhibited, the amount of fat absorbed gets less. The drug has no effect on carbohydrates or protein.
How Effective is Xenical?
The clinical studies data shows that Xenical is effective for the weight-loss therapy. Half a year of the drug's intake combined with dieting has on average resulted in 12.4-pound weight-loss (only dieting brought 6.2-pound result). In the period of year-long treatment, people had lost on average 13.4 pounds (the figure equaled at 5.8 pounds for those just dieting). After a year of treatment, the patients treated with Xenical experienced a drop in total cholesterol, LDL cholesterol, blood sugar and blood pressure rates. Those not taking it had the opposite results.
Those suffering from the type 2 diabetes, under the influence of the drug experienced the improvement of several measures of diabetes control, for instance glucose and hemoglobin A1. This allowed them to reduce the dosage or stop taking certain diabetes medicines. The data also showed that the drug might be the means of preventing type 2 diabetes in people suffering from obesity.
Among the people who took the drug to keep off the weight they had previously lost, only 26 percent gained it back, if compared to 52 percent of people not undergoing the therapy.
How Do I Take Xenical?
In this section you can find some general advice on how and how often Xenical should be taken.
- Xenical is manufactured in the form of capsules, which are usually scheduled to be taken orally with each meal containing fatty food. The intake may be as frequent as three times a day.
- In case the meal is skipped or it does not contain any fat, the dose of Xenical should be skipped as well.
- To produce the desired effect the intake of the drug should be accompanied with a diet low in calories and fats. Taking too much fatty food makes higher the risk of side effects development. Precisely, the calories taken in the form of fat should constitute 30 percent of the total daily amount of calories.
- Do not violate the prescription, if you want the drug to work as intended.
Xenical Dosage
Prescribed Xenical dosage does not depend on such factors as age and weight of the patient or on the other medications taken or medical conditions existing. The recommended dose would always be the same.
Possible Side Effects of Therapy with Xenical
Xenical usage, as the one of any other drug, is not free of side effects, though it is not always that they are observed. Even on the contrary, most of the patients going through the Xenical therapy do not experience any at all. If side effects are still observed, they are mostly of minor type, requiring no medical help or just some simple treatment by healthcare provider.
Below there is a short list of most widespread possible side effects of Xenical:
- Oily spotting (uncontrolled anal seepage of oil)
- Abdominal pain (stomach pain)
- Urgent need to have a bowel movement
- Gas with discharge (of either oil or stool).
Possible Drug Interactions with Xenical
The list of medications and substances that Xenical® (orlistat) can possibly interact with, causing the change in the medications' effectiveness and in their level in the blood, includes but is not limited to:
- Amiodarone (Cordarone®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Diabetes medications
- Thyroid medications, including:
- Liothyronine (Cytomel®)
- Liotrix (Thyrolar®)
- Levothyroxine (Levoxyl®, Synthroid®, Unithroid®)
- Thyroid (Armour® Thyroid, Nature-Throid®)
- Vitamins
- Warfarin (Coumadin®, Jantoven®).
What Medical Conditions Can Serve as a Contra-Indication to Using Xenical?
Before starting the treatment with Xenical you must inform your therapist about the following medical conditions in case you have any:
- Diabetes
- A thyroid disorder
- A history of organ transplantation
- A medical problem that decreases your ability to absorb food
- Gallbladder problems
- Kidney stones in the past
- The history of having pancreatitis.
Be sure as well to mention to you therapist if you are:
- Pregnant or going to get pregnant in nearest future
- Breastfeeding a baby.
It's also important that you should inform your doctor about the other drugs, prescribed or non-prescribed, you're taking on the regular basis. Vitamins and herbal supplements should also be included in the list.
What Should I Do in Case of Overdose with Xenical?
The clinical studies have not shown any particular symptoms of overdose which can be differentiated from the usual side effects apart from that they are of different force and might take more severe forms. In case you face a Xenical overdose, immediately call for professional medical help.
How Should I Store Xenical?
Xenical capsules should be stored in a proper container not allowing the air to contact with pills, at room temperature and spared from humid and heated environments. Make sure it is stored out of children's reach.
What Should I Do in Case I Miss a Dose of Xenical?
If it happened so that you've missed a dose of Xenical, take one if it is less that an hour after the meal in the course of which you were supposed to take it. If the time period is more than an hour, skip the dose you've missed and then take the next according to your prescription. Never double the dose taken in attempt to catch up with your schedule.
Available Forms of Xenical
Xenical is produced in one strength – Xenical 120 mg capsules – only.
Is Xenical Available in the Form of a Generic Medication?
At the moment there is just licensed brand-name version of Xenical available for purchase. Generic Xenical is not sold.
Can I Purchase Xenical without a Prescription?
Xenical is available in its over-the-counter version, which is sold under the brand-name of Alli™, which is a drug lower in strength and containing only half of the dose of orlistat if compared with Xenical.
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