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Lipitor
Lipitor, a drug available on prescription, used in anti-cholesterol and anti-triglycerides treatment, as well as a part of cardiovascular disease prophylaxis. As Lipitor belongs to the class of medical substances called statins, which are capable of blocking the enzyme, responsible for the control of the body cholesterol production. Lipitor side effects occur in the form of headaches, diarrhea, joint and muscle pain.
What Is Lipitor And How Does It Work?
Lipitor® (atorvastatin calcium), available on prescription, is a drug licensed to cure heart-related disorders, such as high cholesterol and high triglycerides level.
Who Manufactures Lipitor?
Lipitor is produced by Pfizer.
What are the Medical Conditions Treated With Lipitor?
Lipitor is approved of being used to pursue the following medical aims:
- Reducing the level of cholesterol (treatment of hypercholesterolemia)
- Reducing the level of triglycerides
- Prevention of heart or blood vessel disease (known as cardiovascular disease).
In What Way Does Lipitor Work?
Belonging to the class of statins (also known as HMG-CoA reductase inhibitors), Lipitor produces the effect based on blocking out the HMG-CoA reductase, the one responsible for the control of the amount of cholesterol produced in the human body. As a result, less cholesterol is made buy the liver. This is not the only effect though. The others produces by Lipitor are as follows:
- It stimulates the liver's ability to collect and utilize the harmful LDL cholesterol
- It prompts the amount of healthy HDL cholesterol.
- It reduces the amount of triglycerides.
What Effects Does Lipitor Have?
High cholesterol treatment is not generally reduced to taking pills. It mostly involves changes in lifestyle i.e. diet, regular exercise, loosing weight, that can possibly lower the cholesterol level. If those fail to produce desired effect, medicines as Lipitor or similar might be prescribed.
Any drug of this kind aims at reducing the level of harmful LDL cholesterol, so that there would be no risk of becoming prone to heart disease or heart attack. For those already belonging to the group of risk, the LDL goal amount should be as low as possible.
Being able to reduce the risk by lowering total cholesterol level as well as the LDL cholesterol level and boosting HDL level, Lipitor reduces the risk of getting any health dysfunctions caused by cholesterol.
The clinical studies showed, that the average raise of healthy HDL cholesterol people undergoing treatment with Lipitor 10 mg was leveled at 6 percent, the decrease of LDL cholesterol by 39 percent, of total cholesterol level – at 29 percent, triglycerides at 19 percent, and this effect was greater is bigger doses of the drug were applied.
How Do I Take Lipitor?
Usually, the recommendations on Lipitor intake schedule and dosage happen to be the following:
- Produced in the form of pills for oral intake, Lipitor is prescribed to be taken once a day, independently of meals, in the course of one or followed by a glass of water.
- The time of day when the dose is taken is insignificant, thought it should be the same time every day, so that the concentration of the drug in your blood would stay stable.
- Swallow the whole pill. It is not intended to be chewed, broken or crushed.
- Stick to the prescription. Do not interrupt or take long breaks from the treatment or it would not produce the desired effect.
Does Lipitor Require Special Diet?
Lipitor does not go well with grapefruit juice, as, if taken simultaneously, the latter provokes the increase in the concentration of Lipitor in your blood, as thus prompts the possibility of having muscle problems. For those who do not want to abstain from drinking grapefruit juice it is better to ask their therapist to choose some other cholesterol-lowering drug.
Lipitor as well requires low-fat and low-cholesterol diet, which is necessary for any course of anti-cholesterol treatment.
Lipitor Dosage
There following factors might influence the doctor's prescription:
- The age of the patient
- The type of medical condition under treatment
- Other drugs taken in
- Other dysfunctions the patient has.
Be careful with the dose you take and never change it on your own unless you have instructions of your therapist to.
Possible Side Effects of Therapy with Lipitor
There's a list of side effects that might appear as a result of Lipitor intake. Though, as it is always the case, not every patient encounters them, on the contrary, as Lipitor is a well-tolerated drug, most of the side effects surfacing during the treatment are minor, which means they do not require any special medical help, apart from that of your doctor, or even might be cured by the patient himself.
The list below includes the most common side effects:
- Muscle pain
- Diarrhea
- Joint pain
- Unexplained rash
- Stomach pain.
Be sure to notify your therapist if you feel sudden pangs of pain, weakness or fatigue, accompanied with the rise of the body-temperature and feeling unwell.
Possible Drug Interactions with Lipitor
Lipitor® (atorvastatin calcium) has a potential of interacting with various kinds of drugs, such as birth control pills, fibrates, and fluconazole, also drugs containing niacin or digoxin. The fuller list comes below:
- Oral contraceptives
- Certain antifungal medications, including:
- Fluconazole (Diflucan®)
- Ketoconazole (Nizoral®)
- Itraconazole (Sporanox®)
- Cimetidine (Tagamet®)
- Clarithromycin (Biaxin®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Digoxin (Digitek®, Lanoxin®, Lanoxicaps®)
- Diltiazem (Cardizem®, Cardizem CD®, Cardizem LA®, Cartia XT®,Dilacor XR®, Dilt-CD®, Diltia XT®, Dilt-XR®, Taztia XT®, Tiazac®)
- Fibrates (such as Lopid®, TriCor®, Triglide™, Antara™, Lofibra®, Lipofen™)
- Grapefruit juice
- Niacin (nicotinic acid, Niacor®, Nicolar®)
- Other statin medications, such as:
- Fluvastatin (Lescol®, Lescol® XL)
- Lovastatin (Altoprev™, Mevacor®)
- Pravastatin (Pravacol®)
- Simvastatin (Zocor®)
- Rosuvastatin (Crestor®)
- Protease inhibitors, such as:
- Amprenavir (Agenerase®)
- Atazanavir (Reyataz®)
- Darunavir (Prezista®)
- Fosamprenavir (Lexiva®)
- Indinavir (Crixivan®)
- Lopinavir and ritonavir (Kaletra®)
- Nelfinavir (Viracept®)
- Ritonavir (Norvir®)
- Saquinavir (Fortovase®, Invirase®)
- Tipranavir (Aptivus®)
- Red yeast rice
- Spironolactone (Aldactone®, Aldactazide®).
What Medical Conditions Can Serve as a Contra-Indication to Using Lipitor?
You should inform your doctor if you have any conditions out of the following:
- Heart disease
- Liver disease or liver failure
- Kidney disease or kidney failure
- Diabetes
- Hypercholesterolemia in your family history
- Had a heart attack or stroke.
Don't forget to let your doctor know if you are:
- Pregnant or planning to get pregnant in near future
- Planning to undergo a procedure or surgery
- Drinking alcohol.
As well give him the fullest information possible on what drugs, controlled or available on free sale, vitamins, antacids, herbal food additives you take at the moment.
What Should I Do in Case of Overdose with Lipitor?
In case you overdose, run for immediate professional medical help.
How Should I Store Lipitor?
Lipitor should be stored at the room temperature away from moisture, and out of children's reach.
What Should I Do in Case I Miss a Dose of Lipitor?
Take your dose as soon as you remember that you've missed one, unless it is time for the next, in which case just continue according to your usual scheme. Never double a dose to make up for the one you've skipped.
What Strengths of Lipitor Are Available?
Lipitor is available for purchase in the following strengths:
- Lipitor 10 mg
- Lipitor 20 mg
- Lipitor 40 mg
- Lipitor 80 mg.
Is Lipitor Available in the Form of a Generic Medication?
Now there's no Lipitor in the form of a generic medication.
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