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Diazepam
Diazepam is a medication that has been licensed for the treatment of anxiety, alcohol withdrawal, cramps, muscle spasms, and seizures. Its effect is based on its influence on the chemical components of the brain tissue, namely gamma-aminobutyric acid (GABA). Even though generally people undergoing the treatment with Diazepam do not face side effects, the latter might occur in the form of sleepiness, weariness and coordination problems. Both the brand-name form and the generic one are available.
What Is Diazepam and How Does It Work?
Diazepam (Valium®) is a drug available on prescription, which is licensed to be used in the treatment of the following medical conditions:
- Anxiety
- Alcohol withdrawal
- Muscle spasms
- Seizures (when used along with other seizure medications).
Possible Side Effects of Therapy with Diazepam
Being a drug, Diazepam, can produce certain side effects. However it is not necessarily that every patient experiences them, even on the contrary it is a drug that is usually well-tolerated and in most cases when it does produce side effects they are minor and might be cured by the patient himself or his healthcare provider. The list below names the most common side effects:
- Sleepiness and drowsiness
- Weariness and fatigue
- Coordination problems.
What Medical Conditions Can Serve as a Contra-Indication to Using Diazepam?
Before taking Diazepam make sure to notify your healthcare provider if you experience any of the following medical conditions:
- Glaucoma
- Former drug- or alcohol – addiction
- Depression
- Liver failure or any other liver dysfunction including cirrhosis
- Kidney dysfunctions including kidney failure
- Lung or breathing dysfunctions
- Any allergies, including those to food, dyes or preservatives.
Also don't forget to mention to your healthcare provider if you are:
- Pregnant or planning to get pregnant in near future
- Breastfeeding a baby.
Also let your healthcare provider know what other medications you take, including those belonging to the group of controlled as well as over-the-counter ones, vitamins and herbal supplements.
In What Way Does Diazepam Work?
Diazepam is the representative of the benzodiazepine group of drugs. The medications of this kind are known to be able to produce the following effects on the human body:
- Reducing the intensity of anxiety
- Causing sleepiness
- Producing relaxing effect on muscles
- Stopping and preventing seizures
- Impairing short-term memory.
All the benzodiazepines produce the effects named above, and depending on the type of the pills you take the degree of this or that effect might vary. The medications of this group influence the chemical components of the brain tissue, namely gamma-aminobutyric acid (GABA), intensifying its natural calming effect and its ability to restrain, block or make slower certain nerve signals produced by brain cells. Working this way, Diazepam as well as other benzodiazepines belongs to the group of sedatives and mild tranquilizers, or as it is also named, the group of central nervous system depressants (CNS depressants).
How Do I Take Diazepam?
Generally the advice on the intake schedule and dosage of Diazepam is the following:
- The drug is generally available in three forms of pills, oral liquid and injections. If the pills are used, they are usually prescribed to be taken three or four times a day (the frequency of intake might vary though)
- The time doesn't usually depend on the food intake, but if the medication causes any kind of stomach discomfort, it might be as well an option to take it together with food during a meal.
- To reach the desired effect you should carefully follow the prescription, as overdose or prolonged treatment course is capable of seriously damaging your health.
Diazepam Dosage
There are a number of factors which might influence the prescription of your healthcare provider. They are as follows:
- The kind of medical condition under treatment
- The age of the patient
- Other drugs taken in along with Diazepam
- Other dysfunctions the patient has.
It is recommended to stick to the dosage prescribed by your healthcare provider and not adjust it without his instruction to or his permission.
Possible Drug Interactions with Diazepam
There are a number of drugs that can cause unwanted effects due to the interaction with Diazepam (Valium®), among which are anesthetics, alcohol-containing substances and antipsychotic medications. The result of the drug interaction might be the change of concentration of diazepam in your blood which may consequently provoke certain side effects (i.e. confusion or memory failure). Discuss possible drug interactions with your healthcare provider.
The substances and drugs which may interact with Diazepam are listed below:
- Alcohol
- Anesthetics
- Antidepressant medications
- Antipsychotic medications, such as:
- Aripiprazole (Abilify®)
- Chlorpromazine (Thorazine®)
- Clozapine (Clozaril®, FazaClo®)
- Fluphenazine (Prolixin®)
- Olanzapine (Zyprexa®, Symbyax®)
- Perphenazine (Trilafon®)
- Paliperidone (Invega®)
- Quetiapine (Seroquel®)
- Risperidone (Risperdal®)
- Thioridazine (Mellaril®)
- Trifluoperazine (Stelazine®)
- Ziprasidone (Geodon®)
- Amobarbital (Amytal®)
- Butalbital (Fioricet®, Fiorinal®)
- Pentobarbital (Nembutal®)
- Phenobarbital (Luminal®)
- Secobarbital (Seconal®)
- Grapefruit juice
- Narcotics or opiates, such as morphine, oxycodone, or hydrocodone (Lortab®, Vicodin®)
- Other benzodiazepines, including:
- Alprazolam (Xanax®)
- Chlordiazepoxide (Librium®, Limbitrol®, Librax®)
- Clonazepam (Klonopin®)
- Clorazepate (Tranxene®)
- Estazolam (ProSom®)
- Flurazepam (Dalmane®)
- Lorazepam (Ativan®)
- Midazolam (Versed®)
- Temazepam (Restoril®)
- Triazolam (Halcion®)
- Probenecid
- Seizure medications
- Sleep medications.
What Should I Do in Case of Overdose with Diazepam?
Overdose of the drug results in:
- Confusion
- Drowsiness
- Coma
- Slow reflexes.
If you suffer an overdose, call for immediate professional medical help.
What Should I Do in Case I Miss a Dose of Diazepam?
In case a dose of Diazepam is missed, it should be taken as soon as you remember this. If it is close to the time when you have to take the next dose, then skip the missed one and stick to your usual schedule. Never take a double dose of Diazepam trying to make up for the skipped one.
Who Manufactures Diazepam?
The manufacturer of Diazepam is Roche Products, Inc.
What Strengths of Diazepam Are Available?
There're currently three strengths of Diazepam available:
- Diazepam 2 mg
- Diazepam 5 mg
- Diazepam 10 mg.
Is Diazepam Available in the Form of a Generic Medication?
At the moment Diazepam is available both in the form of a brand-name and generic medication.
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