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What Cytoxan is taken for

Cytoxan (cyclophosphamide) is a cancer medication that can also be used for the treatment of certain conditions in children (kidney-related ones). This medicine works by interfering with the growth and spread of cancer cells in the body. Your doctor may prescribe this drug for other conditions you may have (off-label use) or recommend combining it with some other treatments for best effects.

Discussing Cytoxan treatment with your health care provider

Treatment with Cytoxan must be supervised by a qualified health care professional to make sure this drug works well. There are some health issues associated with taking this medicine in individual patients, such as allergic reactions, bladder problems, blood problems, and decreased bone marrow function, and a few other ones. You will need to discuss your personal risk for developing those problems before starting to use Cytoxan. You need to talk to your doctor before the treatment can be started and report any medical conditions or health issues you have or used to have that may affect the success of your treatment in any way. Please make sure you always let your doctor know if you have any of the following: unhealed wounds, kidney disease, any infection, bone marrow problems, a history of heart disease, liver disease, low level of white blood cells, no adrenal glands, or recent vaccinations.

How to start taking Cytoxan

You will need to use Cytoxan exactly as recommended by your health care provider, usually with a full glass of water. In general, you will need to get plenty of fluid during the day to avoid urinary bladder irritation, as well as empty your bladder as frequently as possible (approximately every 2 to 3 hours, even at night). The dose of Cytoxan and its form depend on the type of cancer being treated, and a number of other individual factors. It's best to take each dose on an empty stomach, although in case you get stomach upset, you can take it with some food. You will need to carry on using Cytoxan even if you get nausea and vomiting, and change anything in your treatment only if recommended to do so by your health care provider. You will need to avoid contacts with people that have any contagious illnesses and try to stay away from places where there are too many people, as some of them may have an infection.

Are there any side effects to be aware of?

You will need to contact your health care provider if you experience any of the following serious side effects, or seek emergency medical help if you are unable to contact your doctor: sore throat, closing of your throat, chills, unusual bleeding or bruising, painful or difficult urination, blood in the urine, chest pain, lower back pain, difficulty breathing, yellowing of the skin or eyes, as well as black or tarry stools. Milder side effects of Cytoxan still need to be discussed with your doctor to see if you need to do anything about them, especially vomiting, mouth sores, diarrhea, temporary hair loss, rash, changes in skin color, changes in nails, abdominal pain, nausea or decreased appetite. Your doctor may want to monitor you closely for side effects of adjust your dose to make sure you get the most out of your treatment.

If an overdose occurs

If you happened to overdose, seek emergency medical help and report any symptoms that appeared after you took too much. The following are most commonly reported symptoms of Cytoxan overdose: infection, heart problems, and decreased bone marrow function.

How Cytoxan can affect your unborn child

Cytoxan is FDA pregnancy category D: it will harm an unborn child if taken by a pregnant woman. This medicine can also affect the pregnant woman by interfering with egg production, and affect sperm production in males. You are not supposed to start using Cytoxan if you are pregnant or breastfeeding without first discussing everything with a qualified health care professional. Males using Cytoxan must also be very careful, as the baby can be affected at conception even if the mother did not take the medicine. Cytoxan can harm an unborn child, as it passes into breast milk. Breastfeeding is therefore rarely justified.

Combining Cytoxan with other treatments

Cytoxan can interact with the following medications: phenobarbital, other chemotherapy medicines, digoxin, thiazide diuretics, or warfarin. This list is by no means complete, as there may be other drugs that can interact with Cytoxan. You doctor needs to be aware of any other drugs you are using, as well as any prescription or over-the-counter products taken, as some of them can't be combined with Cytoxan.

If you miss a dose of Cytoxan

You are not supposed to miss doses of Cytoxan, as this may affect the success of your treatment. If you remembered about the missed dose soon enough, you can still take it and carry on with the treatment. The dose missed is supposed to be skipped if you need to take the next one very soon.