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Avandia
Avandia is a prescription medication used to cure type 2 diabetes by improving insulin sensitivity and decreasing the level of sugar in blood, thus properly controlling it. The drug is available in the form of pills that you should take by mouth once or twice daily. The dosage will be adjusted by your therapist and will depend on different factors, including the medical conditions you may have, the type of diabetes treatment you are undergoing, other drugs you use at the moment. Just like other medicines, Avandia may cause some side effects, which include migraine, upper respiratory infections, pain in the back.
What is Avandia and What Is It Used for?
Avandia® (rosiglitazone maleate) is licensed for the treatment of type 2 diabetes, which is also called noninsulin-dependent diabetes (or adult-onset diabetes). You may take it independently or in combination with some other drugs treating diabetes.
However, the medication isn't effective for curing type 1 diabetes.
The medication belongs to the class of thiazolidinediones, also called "glitazones", which are known for their effectiveness in the treatment of diabetes. It is responsible for the increase of insulin sensitivity, helping your organism use insulin properly. Avandia reduces blood sugar levels.
Who Manufactures Avandia?
Avandia is produced by GlaxoSmithKline.
In What Way Does Avandia Work?
The research carried out by the specialists revealed the effectiveness of Avandia treating type 2 diabetes.
Avandia and Hemoglobin Alc
HbAlc (Hemoglobin Alc) measures sugar in blood. For those who don't suffer from diabetes, Hemoglobin Alc rates are always not more than 5 %, unlike people who have diabetes, having higher showings. The research revealed that Avandia helped people taking it reduce HbAlc showings by up to approximately 0.7%. At the same time, the concentration of HbAlc in the blood of those not taking this medication increased by 0.8%.
It's proven that high HbAlc increases the risk of diabetes development and such diabetes-induced conditions as heart disorder, diabetic retinopathy and neuropathy, diabetic nephropathy. Taking Avandia, you keep your blood sugar under control, thus lowering the risk of suffering from these disorders.
Avandia and Fasting Blood Sugar
The effectiveness of Avandia may be also revealed with fasting blood sugar. People who do not take the drug usually have increased fasting blood sugar while the ones taking Avandia report the lowering of their level of fasting blood sugar by 25 to 55mg/dL.
The clinical research showed that the patients taking the medication gain approximately 2 to 12 pounds. Avandia may also affect good cholesterol and bad cholesterol levels.
How Do I Take Avandia?
While taking Avandia, consider the following issues:
- Avandia is available in tablets that you should tae by mouth once or twice daily
- People may take it without food, but in case of stomach discomfort they are recommended to take it during a meal
- In order to keep its level even in your blood, take Avandia regularly at the same time of the day
- Follow the prescription, otherwise it won't work properly. Its effects will stop as soon as you stop taking the drug.
Avandia Dosage
The dosage adjusted by your doctor depends on such factors as:
- The type of diabetes therapy you are undergoing
- Other medical disorders you may suffer from
- Other drugs you're taking.
Don't try to change your dosage without therapist's recommendations.
Possible Side Effects of Therapy with Avandia
Generally, all medicaments may cause side effects. Avandia is not an exception, and some people taking it may have certain minor side effects. However, Avandia is usually well-tolerated and serious side effects are extremely rare.
Common side effects comprise:
- Migraines
- Cold
- Broken bones
- Swelling or gain of water weight
- Back pain
- Injury.
Possible Drug Interactions with Avandia
The list of medications that Avandia can potentially interact with includes:
- Atazanavir (Reyataz®)
- Certain seizure medications, including:
- Carbamazepine (Tegretol®)
- Fosphenytoin (Cerebyx®)
- Phenobarbital (Luminal®)
- Phenytoin (Dilantin®)
- Primidone (Mysoline®)
- Gemfibrozil (Lopid®)
- Rifampin (Rifadin®) or rifapentine (Priftin®)
- Ritonavir (Norvir®).
What Medical Conditions Can Serve as a Contra-Indication to Using Avandia?
Before taking the medicine tell your doctor if you suffer from:
- Any heart disorders (including congestive heart failure)
- Liver disease (such as liver failure, cirrhosis)
- A condition requiring surgery in nearest future
- Allergies (to food, dyes, etc.).
Please don't forget to inform the therapist in case you are:
- Pregnant or making attempts to become pregnant
- Experiencing difficulties getting pregnant
- Breastfeeding
- Pre-menopausal, having irregular menstrual periods.
Inform the doctor about all the medications you are taking.
Is There Any Alternative to Therapy with Avandia?
You may start treating type 2 diabetes by changing your lifestyle, for instance start with loss of weight, diets, special exercise. In case such changes are not effective, Avandia shall be helpful.
Avandia aims at decreasing the level of blood sugar thus lowering the risk of diabetes-related issues, including problems with heart, nerves, kidney, eyes.
Avandia is helpful for many patients, as it allows controlling blood sugar. Most people tolerate it without any problems. In case the drug causes side effects or doesn't work properly, try to take it in combination with metformin (Glucophage®) or insulin. The substitutes for Avandia are thiazolidinediones.
What Should I Do in Case of Overdose with Avandia?
As it's revealed by the research, doses of Avandia up to 20 mg don't cause serious side effects. There are no typical symptoms of overdose. In case you happen to take too much of Avandia, contact your therapist.
How Should I Store Avandia?
We recommend you to store the drug at room temperature, away from the reach of children. It should be kept in a dry, airtight container.
What Should I Do in Case I Miss a Dose of Avandia?
If you happen to forget to take a dose on time, take it when you remember. Never take a double dose.
Available Forms of Avandia
The medication comes in different strengths:
- Avandia 2 mg tablets
- Avandia 4 mg tablets
- Avandia 8 mg tablets.
Is Avandia Available in the Form of a Generic Medication?
Currently the drug is not available in generic version.
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